
Source: Men's Living Jan 2009
Exercise Your Mind
Canadians should not eat a brand of chocolate-dipped honey peanut bar, the latest salmonella-linked product that's part of a growing recall of peanut products in the United States.
The Canadian Food Inspection Agency said it has expanded a voluntary recall to include another snack food made in the U.S.
Isagenix's Chocolate Dipped Honey Peanut IsaLean Bar in 2.29 oz or 65 gram size contains peanut butter or peanut paste recalled in the U.S. by Peanut Corporation of America, CFIA said.
The bars may have been distributed nationally, the agency said.
No reported illnesses are associated with consumption of the bars.
Investigators in the U.S. have traced the outbreak of Salmonella typhimurium to a peanut processing plant in Blakely, Ga.
More than 400 kinds of cakes, cookies, ice cream, other snack foods, Asian-style sauces and dog biscuits have been recalled in the outbreak.
More than 500 people in the U.S. have fallen ill in the outbreak, which may have contributed to eight deaths.
On Wednesday, the Peanut Corp. expanded its recall to all peanut products produced at the Georgia plant since Jan. 1, 2007, as a precaution.
"We have been devastated by this, and we have been working around the clock with the FDA to ensure any potentially unsafe products are removed from the market immediately," Peanut Corp. of America president Stewart Parnel said in a statement late Wednesday.
Company officials are co-operating with state and federal officials, he added.
There have been calls for a criminal investigation into the company, but the U.S. Food and Drug Administration has said that is premature and the agency's investigation continues.
"We feel very confident that it's one of the largest recalls we've had," said Stephen Sundlof, head of the FDA's food safety centre. "We're still in the process of identifying products, but it certainly is among the largest."
The expanded recall includes contamination with salmonella strains not associated with the current outbreak, Sundlof told a telephone briefing with reporters.
"The additional salmonella strains discovered at this plant underscore that this plant was shipping adulterated product, but as for now we are not aware of any illnesses connected to any other salmonella strains shown at this facility," Michael Rogers, head of FDA's field investigations, told reporters.
FDA inspection reports showed problems including live cockroaches, mould and signs of a leaking roof at the Georgia plant.
Bisphenol A, a chemical used to make many hard plastic products, may stay in the body longer than previously thought.
Researchers say the finding may also mean that people are ingesting the chemical from non-food sources.
In Wednesday's online issue of the journal Environmental Health Perspectives, Dr. Richard Stahlhut of the University of Rochester's Environmental Health Sciences Center said high levels of BPA remained in the body after people in a study fasted for as long as 24 hours.
In October 2008, Canada became the first country in the world to ban the import and sale of polycarbonate baby bottles containing bisphenol A, citing concerns about exposing infants to the chemical.
Late last year, the U.S. Food and Drug Administration said it planned more research into the safety of BPA, but the agency indicated no immediate plans to follow Canada's curb on the chemical.
In the latest study, Stahlhut and his colleagues looked at BPA levels in the urine of 1,469 U.S. adults who took part in a government health survey.
The researchers said they expected to see a relationship between the last meal, fasting time and BPA levels.
Based on the assumption that BPA is excreted quickly and people are exposed to the chemical mainly through food, much lower BPA levels were expected among those who fasted for 24 hours than those who fasted for 8.5 hours.
"Our results simply do not fit that picture," said Stahlhut.
"The research community has clues that could help explain some of these results, but to date the importance of the clues have been underestimated. We must chase them much more vigorously now."
BPA levels appeared to drop about eight times more slowly than expected, he added.
The researchers proposed two possible explanations for the higher-than-expected levels among people who fasted:
"The finding is surprising and a little disturbing, in that all assumptions about the safety of BPA made by regulatory agencies are based on the idea that we are primarily exposed to this from eating," Fred vom Saal, a professor of biological sciences at the University of Missouri-Columbia Division of Biological Sciences, told HealthDay News.
To find out, more research is needed to evaluate the effects of BPA on fat tissue hormones and function, and to compare BPA levels in fat, blood and urine, Stahlhut said.
Bisphenol A is a chemical compound found in some hard, clear, lightweight plastics and resins. It's used in the production of various types of food and drink containers, compact discs, electronics and automobile parts, and as a liner in some metal cans.
Animal studies suggest that, once ingested, BPA may imitate estrogen and other hormones, according to the U.S. National Institutes of Health.
In a study published in September 2008 in the Journal of the American Medical Asssociation, adults with higher BPA levels in their urine were linked to higher risks for heart disease and diabetes.
The American Chemistry Council, which represents makers of BPA, maintains that the chemical is safe for all uses. Steven Hentges, spokesman for the trade group, dismissed the study's conclusions as "speculative at best."
Source: CBC.ca
Taking two commonly prescribed blood-pressure drugs in combination can trigger severe heart and kidney problems, according to an alert issued Friday to patients and physicians.
The drugs, angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers, are considered safe and effective on their own and when combined with other hypertension drugs, but ACE inhibitors and ARBs should not be used together, the Heart and Stroke Foundation is warning.
The group estimates that about 175,000 Canadians – most of them over the age of 65 – are taking this particular combination of drugs.
“This is a safety issue that the public and practitioners need to be aware of,” said Sheldon Tobe, a nephrologist at Sunnybrook Health Sciences Centre in Toronto. “Bringing blood pressure under control is very important, but with this particular combination the potential risks outweigh the benefits.”
Margaret Moy Lum-Kwong, director of high-blood-pressure strategy at the Heart and Stroke Foundation of Ontario, stressed that patients should not stop taking medications, even if they are taking ARBs and ACE inhibitors together, but discuss the matter with their physician.
“If you are on this particular combination treatment … go directly to your doctor for an alternative treatment,” she said.
High blood pressure, the leading risk factor for heart disease, is commonplace, affecting one in four men and one in five women.
A person is considered hypertensive with a blood-pressure reading of 140/90 millimetres of mercury (mmHg) or higher. Healthy adults should have a blood pressure in the range of 120/80 mmHg, although that target varies with age and other health conditions such as diabetes.
According to a study published last year, about 85 per cent of those with high blood pressure are aware of their condition and most are being treated successfully.
Blood pressure can often be controlled with lifestyle changes such as weight loss, healthy eating (particularly reducing salt consumption) and exercise, but many Canadians are treated with prescription drugs.
About two-thirds of hypertensive cases are treated with combinations of drugs, including diuretics, ACE inhibitors, ARBs and calcium channel blockers.
The safety and effectiveness of various combinations is being studied systematically. Last year, a landmark Canadian-led study showed that the combination of an ACE inhibitor and ARB was only marginally more effective at lowering blood pressure than either drug taken alone.
But it also revealed far more side effects among those taking the ACE-ARB combo, including fainting, diarrhea and dangerously elevated potassium levels that could result in kidney failure (and the need for dialysis) and even death.
Dr. Tobe stressed that severe complications were rare, but said there is no justification for putting patients at risk when there is no additional benefit.
“What we're doing here is refining therapy to make it safer,” he said.
Arthur Innes, a 57-year-old Torontonian who works in a long-term care facility, said he got his blood pressure checked as part of a physical for life insurance and was shocked to learn readings were dangerously high at 200/90 mm/Hg.
His family doctor prescribed a combination of ARB and ACE inhibitor. “These medications didn't make me feel very good. I was dizzy and had nausea all the time,” Mr. Innes said.
He was referred to a specialist and prescribed different medication; he now has his blood pressure under control and suffers no side effects.
“Taking the meds is important for your heart,” Mr. Innes said, “but you don't want medications that impair your way of life.”
Source: theGlobeandMail.ca